ISSN 1662-4009 (online)

ey0017.3-15 | Medication associated thyroid disease | ESPEYB17

3.15. The effects of amiodarone on thyroid function in pediatric and young adult patients

B Barrett , CP Hawkes , A Isaza , AJ Bauer

To read the full abstract: J Clin Endocrinol Metab. 2019;104:5540–5546.This single center, retrospective study analyzed the prevalence and natural history of amiodarone associated thyroid disease in 190 children and young adults with detailed thyroid function tests. Amiodarone induced hypothyroidism (AIH) and thyrotoxicosis (AIT) are well known entities due to direct thyroid toxicity. Further, subclinical hypothyroidism (SCH) is caused by a...

ey0016.3-7 | Congenital Hypothyroidism | ESPEYB16

3.7. Incidence of congenital hypothyroidism over 37 Years in Ireland

N McGrath , CP Hawkes , CM McDonnell , D Cody , SM O'Connell , PD Mayne , NP Murphy

To read the full abstract: Pediatrics. 2018;142(4). pii: e20181199.This unique study investigated the incidence of congenital hypothyroidism from the start of the newborn screening in 1979 to 2016. The authors report a marked increase in incidence from 0.27 cases per 1000 live births in 1979–1991 to 0.41 in 1992–2004 and 0.65 in 2005–2016.A major str...

ey0019.2-6 | Neonatal hypoglycaemia | ESPEYB19

2.6. The bihormonal bionic pancreas improves glycemic control in individuals with hyperinsulinism and postpancreatectomy diabetes: a pilot study

A Rayannavar , LM Mitteer , CA Balliro , FH El-Khatib , KL Lord , CP Hawkes , LS Ballester , ER Damiano , SJ Russell , DD De Leon

Diabetes Care. 2021 Nov;44(11):2582-2585. doi: 10.2337/dc21-0416. PMID: 34518377.Brief Summary: This pilot study, in patients with post-pancreatectomy diabetes due to congenital hyperinsulinism, assessed pump-delivered insulin and glucagon (Bihormonal Bionic Pancreas, BHBP) to regulate blood glucose levels. BHBP controlled post-prandial glucose levels better than a conventional insulin pump but fur...